Effects of TNFα receptor TNF-Rp55- or TNF-Rp75- deficiency on corneal neovascularization and lymphangiogenesis in the mouse
نویسندگان
چکیده
منابع مشابه
Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice.
PURPOSE Tumor necrosis factor (TNF)-alpha is one of the major cytokines in inflammation and apoptosis. It has been demonstrated that inhibition of TNFalpha can reduce leukocyte adhesion, vascular leakage, and apoptotic endothelial cell death in diabetes. This study was conducted to investigate the effect of TNF-Rp55 and TNF-Rp75 on retinal development in oxygen-induced retinopathy. METHODS TN...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2021
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0245143